Fig. 4

Differential gene expression of dopamine-treated human microglia. A Dopamine induced both up-regulated (776) and down-regulated (828) genes (fold change >|1.1| and FDR < 0.05) in C20 microglia. Violin plots showing the relative expression of genes in the two different conditions (vehicle or dopamine), including (B) genes previously found to be upregulated by dopamine in myeloid cells, (C) genes associated with modulation inf inflammation, (D) genes associated with regulation of dopaminergic signaling, (E) genes associated with Wnt signaling, and (F) genes associated with microglia identity and activation